Zusammenfassung
Pachychoroidale Erkrankungen umfassen eine Gruppe von Erkrankungen, die charakteristische
choroidale Merkmale zeigen. Diese können heutzutage durch multimodale Bildgebung immer
differenzierter beschrieben werden und umfassen fokale oder diffuse Aderhautverdickungen
mit erweiterten und hyperpermeablen choroidalen Gefäßen. Die richtige Diagnose und
Abgrenzung von
anderen exsudativen Erkrankungen ist für eine mögliche Therapie von großer Bedeutung.
Abstract
Pachychoroid spectrum disorders include uncomplicated pachychoroid, pachychoroid pigment
epitheliopathy, central serous chorioretinopathy, pachychoroid neovasculopathy, polypoidal
choroidal
vasculopathy/aneurysmal type 1 neovascularisation, focal choroidal excavation and
peripapillary pachychoroid syndrome. They are characterized by a thickened and hyperpermeable
choroid and
thinning of the choriocapillaris. The disorders are being diagnosed with increasing
frequency and differentiation due to the advancement of multimodality imaging. Current
understanding of
the development, course, possible complications and treatment of these diseases is
growing rapidly, but not all mechanisms have yet been elucidated. A correct diagnosis
is important,
especially the differentiation between the presence of active neovascularisation or
a purely exudative stage, in order to initiate a therapy. It is also not yet clear
why patients have a
thickened choroid and why some of these patients develop pathological changes such
as subretinal fluid, RPE changes or neovascularisation.
Schlüsselwörter
Aderhaut - Anti-VEGF-Therapie - Chorioretinopathia centralis serosa
Key words
Pachychoroid - anti-VEGF therapy - central serous chorioretinopathy
